Immunoglobulin gene rearrangements in normal mouse B cells.
نویسندگان
چکیده
منابع مشابه
Immunoglobulin gene rearrangements in normal mouse B cells.
We have analyzed the structure of rearranged mu heavy-chain genes obtained from the genomic DNA of normal BALB/c mouse spleen cells expressing surface immunoglobulin M. Examples were found of two types of nonproductive rearrangements, which may be responsible for allelic exclusion in normal B cells. In one of these rearrangements, a germ line D gene segment has joined to the JH4 gene segment bu...
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ژورنال
عنوان ژورنال: Molecular and Cellular Biology
سال: 1982
ISSN: 0270-7306,1098-5549
DOI: 10.1128/mcb.2.7.829